SANDEEP KUMAR AGNIHOTRI
博士，研究助理
Email: sandy@@gdiist.cn
個人簡介：
在尼赫魯大學(xué)完成了博士學(xué)位，在哈爾濱工業(yè)大學(xué)神經(jīng)生物學(xué)和帕金森病實驗室的博士后，之后，Sandeep 博士加入上海中國科學(xué)院（CAS）神經(jīng)科學(xué)研究所（ION）腦科學(xué)與智能技術(shù)卓越中心（CEBSIT），擔(dān)任博士后研究員。Sandeep 博士加入燧人（上海）醫(yī)療科技有限公司是因為他對神經(jīng)科學(xué)領(lǐng)域診斷神經(jīng)退行性疾病的應(yīng)用方面感興趣和熱情。Sandeep 博士獲得了UGC頒發(fā)的優(yōu)秀學(xué)生獎，并在生物技術(shù)碩士期間獲得了全額 DBT（印度生物技術(shù)系）獎學(xué)金
研究方向：
[1] 認(rèn)知神經(jīng)科學(xué)與行為分析
[2] 認(rèn)知障礙對神經(jīng)退行性疾病的診斷
代表論著：
[1] Loss of PTEN-induced kinase 1 regulates oncogenic Ras-driven tumor growth by inhibiting mitochondrial fission. Dantong Zhu, Fengtong Han, Liuke Sun, Agnihotri SK, Ying Hu and Hansruedi Büeler. Frontiers in Oncology Cancer Genetics, 2022, May 5;12:893396. doi: 10.3389/fonc.2022.893396. PMID:35600352
[2] PINK1 deficiency is associated with increased deficits of adult hippocampal neurogenesis and lowers the threshold for stress-induced depression in mice. Agnihotri SK, Liuke Sun, Benjamin K. Yee, Ruifang Shen, Ravi S. Akundi, Lianteng Zhi, Marilyn J. Duncan, Wayne A. Cass and Hansruedi Büeler. BBR.2019 May 2; 363:161-172. doi: 10.1016/j.bbr.2019.02.006.PMID: 30735759
[3] Lack of PINK1 alters glia innate immune responses and enhances inflammation-induced, nitric oxide-mediated neuron death. Sun L, Shen R, Agnihotri SK, Chen Y, Huang Z, Büeler H. Sci Rep. 2018 Jan 10;8(1):383. doi: 10.1038/s41598-017-18786-w. PMID:29321620
[4] Loss of PINK1 leads to metabolic deficits in adult neural stem cells and impedes differentiation of newborn neurons in the mouse hippocampus. Agnihotri SK, Shen R, Li J, Gao X, Büeler H. FASEB J. 2017 Mar 21. pii: fj.201600960RR. doi: 10.1096/fj.201600960RR.PMID: 28325755
[5] Brain most susceptible to cadmium induced oxidative stress in mice. Agnihotri SK, Agrawal U, Ghosh I.J Trace Elem Med Biol. 2015 Apr;30:184-93. doi: 10.1016/j.jtemb.2014.12.008.PMID:25617233.
[6] Cadmium Toxicity Showing Organ Specific Signature of Responsiveness. Agnihotri SK, Ghosh I (2017) Perspectives in Environmental Toxicology. Springer International Publishing, Switzerland p, 203-214.doi: 10.1007/978-3-319-46248-6_4
[7] Mechanistic Effect of Heavy Metals in Neurological Disorder and Brain Cancer. Agnihotri SK, Kesari K.K. (2019) In: Kesari K. (eds) Networking of Mutagens in Environmental Toxicology. Environmental Science and Engineering. Springer, Cham doi: https://doi.org/10.1007/978-3-319-96511-6_2
